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ACTN4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 19096-1-AP-20UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16838864

  • 131.19 CHF / 20 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

This antibody recognizes 100-105 kDa of endogenous ACTN4 protein in various lysates.

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Spezifikation

Spezifikation

ACTN4
Polyclonal
Unconjugated
ACTN4
ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4
Rabbit
Antigen Affinity Chromatography
RUO
60595, 63836, 81
Antibody
IgG
Immunohistochemistry (Paraffin), Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
0.41 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O43707, P57780, Q9QXQ0
Actn4
ACTN4 Fusion Protein Ag13546
20 μL
Primary
Human, Mouse, Rat
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote