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Acetylcholine chloride, 98+%

Product Code. 11321537
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Código de producto. 11321537 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor L02168.14
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Descripción

CAS: 60-31-1 | C7H16ClNO2 | 181.66 g/mol

Acetylcholine chloride acts as an endogenous neurotransmitter at cholinergic synapses. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions. It reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis.The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Acetylcholine chloride acts as an endogenous neurotransmitter at cholinergic synapses. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions. It reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis.The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Solubility
Soluble in water (600 g/L at 20°C), alcohol, DMSO (36 mg/ml at 25°C), and ethanol (36 mg/ml at 25°C). Insoluble in ether.

Notes
Store away from moisture. Store under dry inert gas. Incompatible with heat,oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 60-31-1
Molecular Formula C7H16ClNO2
Molecular Weight (g/mol) 181.66
MDL Number MFCD00011698
InChI Key JUGOREOARAHOCO-UHFFFAOYSA-M
Synonym acetylcholine chloride, miochol, acecoline, chloroacetylcholine, arterocoline, acecholin, ovisot, ach chloride, azetylcholinchlorid, 2-acetyloxy-n,n,n-trimethylethanaminium chloride
PubChem CID 6060
ChEBI CHEBI:2417
IUPAC Name 2-acetyloxyethyl(trimethyl)azanium;chloride
SMILES CC(=O)OCC[N+](C)(C)C.[Cl-]

Especificaciones

Melting Point 149°C to 152°C
Quantity 25 g
Beilstein 3571875
Sensitivity Very Hygroscopic
Merck Index 14,87
Solubility Information Soluble in water (600g/L at 20°C),alcohol,DMSO (36mg/ml at 25°C),and ethanol (36mg/ml at 25°C). Insoluble in ether.
Formula Weight 181.66
Percent Purity ≥98%
Chemical Name or Material Acetylcholine chloride

RUO – Research Use Only

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