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  7. 4',5,7-Trihydroxyflavon, 97 %, Thermo Scientific Chemicals

4',5,7-Trihydroxyflavon, 97 %, Thermo Scientific Chemicals

Product Code. 11368126
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Product Code. 11368126 Supplier Thermo Scientific Alfa Aesar Supplier No. L15041.MC
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Description

CAS: 520-36-5 | C15H10O5 | 270.24 g/mol

4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
4′,5,7-Trihydroxyflavon ist ein nicht mutagenes Flavonoid, das nachweislich die Zellproliferation, Angiogenese und Proteinkinasen hemmt. Induziert die Apoptose von Brustkrebszellen. Hemmt die durch Topoisomerase I katalysierte DNA-Religation und verbessert die interzelluläre Kommunikation über Gap Junctions.

Löslichkeit
Löslich in Dimethylsulfoxid (27 mg/ml) oder 1M Kaliumhydroxid (50 mg/ml).

Hinweise
Kühl lagern. Behälter an einem trockenen und gut belüfteten Ort dicht verschlossen halten. Nicht kompatibel mit starken Oxidationsmitteln.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 520-36-5
Summenformel C15H10O5
Molekulargewicht (g/mol) 270.24
MDL-Nummer MFCD00006831
InChI-Schlüssel KZNIFHPLKGYRTM-UHFFFAOYSA-N
Synonym apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone
PubChem CID 5280443
ChEBI CHEBI:18388
IUPAC-Name 5,7-Dihydroxy-2-(4-hydroxyphenyl)chromen-4-on
SMILES OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1

Specifications

Chemischer Name oder Material 4',5,7-Trihydroxyflavone
Schmelzpunkt ∽315°C (decomposition)
Menge 100 mg
Beilstein 262620
Merck Index 14,730
Löslichkeitsinformationen Soluble in dimethyl sulfoxide (27mg/ml) or 1M potassium hydroxide (50mg/ml).
Formelmasse 270.24
Reinheit (%) 97%

RUO – Research Use Only

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