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Tocris Bioscience™ 2-APB

Artikelnummer. 18075342
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Menge:
10 mg
50 mg
Packungsgröße:
10 Milligramm
50 Milligramm
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18075342 10 mg 10 Milligramm
18034702 50 mg 50 Milligramm
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Artikelnummer. 18075342 Lieferant Tocris Bioscience™ Lieferanten-Nr. 1224/10

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IP3 receptor antagonist. Also TRP channel modulator

A functional and membrane permeable D-myo-inositol 1,4,5-trisphosphate (IP3) receptor antagonist (IC50 = 42 μM). Stimulates store-operated calcium (SOC) release at low concentrations (< 10 μM) and inhibits it at higher concentrations (up to 50 μM). Increases STIM-Orai channel conductance and limits ion selectivity. Modulator of TRP channels; blocks TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8 and TRPP2 and at higher concentrations stimulates TRPV1, TRPV2 and TRPV3. Also blocks specific gap channel subtypes.
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 524-95-8
Summenformel C14H16BNO

Spezifikation

Chemischer Name oder Material 2-APB
Menge 10 mg
Formelmasse 225.1
Reinheit >98%
Molekulargewicht 225.10
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