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Thermo Scientific Chemicals 2',3'-Dideoxycytidin, 98 %

Artikelnummer. 11322906
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Artikelnummer. 11322906 Lieferant Thermo Scientific Chemicals Lieferanten-Nr. L10619.MF
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Beschreibung

CAS: 7481-89-2 | C9H13N3O3 | 211.22 g/mol

2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 7481-89-2
Summenformel C9H13N3O3
Molekulargewicht (g/mol) 211.22
MDL-Nummer MFCD00012188
InChI-Schlüssel WREGKURFCTUGRC-KGQMAECUNA-N
Synonym zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one
PubChem CID 24066
ChEBI CHEBI:10101
SMILES NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1

Specifications

Chemischer Name oder Material 2′,3′-Dideoxycytidine
Schmelzpunkt 216°C to 220°C
Verpackung Glasflasche
Menge 50 mg
Beilstein 654956
Löslichkeitsinformationen Soluble in water (76.4mg/ml at 25°C),DMSO (42mg/ml at 25°C),and ethanol (<1mg/ml at 25°C).
IUPAC-Name 4-Amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-on
Formelmasse 211.22
Reinheit (%) ≥98%
Physikalische Form Fest

Safety and Handling

compliance-icons
Product Identifier
  • 2',3'-Dideoxycytidine
 Signal Word
  • Achtung
 Hazard Category
  • Karzinogenität Kategorie 2
 Hazard Statement
  • H351-Kann vermutlich Krebs erzeugen.
 Precautionary Statement
  • P201-Vor Gebrauch besondere Anweisungen einholen.
  • P280-Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.
  • P308+P313-BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
 Supplemental information
  • MIXTURE LIST-Contain: 2,3-Dideoxycytidine
SDS

RUO – Research Use Only

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