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Trequinsin hydrochloride, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
Extremely potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3; IC50 = 250 pM). Potently inhibits arachidonic acid-induced aggregation of human platelets (IC50 = 50 pM). Orally active antihypertensive agent; reduces systemic blood pressure in both normotensive and hypertensive animal models.
Spezifikation
| Chemischer Name oder Material | Trequinsin hydrochloride |
| CAS | 78416-81-6 |
| Summenformel | C24H28ClN3O3 |
| MDL-Nummer | MFCD01076563 |
| Menge | 10 mg |
| Synonym | trequinsin hydrochloride, trequinsin, hydrochloride, dsstox_cid_25806, dsstox_rid_81144, dsstox_gsid_45806, 4h-pyrimido 6,1-a isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl-2-2,4,6-trimethylphenyl imino-, monohydrochloride, 9,10-dimethoxy-2-mesitylimino-3-methyl-2,3,6,7-tetrahydro-4h-pyrimido-6,1-a-isoquinolin-4-one, hcl, trequinsin hcl, trequinsinhydrochlorid, c24h27n3o3.hcl |
| InChI-Schlüssel | DTCZZBVPTHVXFA-UHFFFAOYSA-N |
| SMILES | [H+].[Cl-].COC1=CC2=C(C=C1OC)C1=CC(=NC3=C(C)C=C(C)C=C3C)N(C)C(=O)N1CC2 |
| IUPAC-Name | hydrogen 9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-2H,3H,4H,6H,7H-pyrimido[4,3-a]isoquinolin-4-one chloride |
| Molekulargewicht (g/mol) | 441.96 |
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