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CEP164 Rabbit anti-Canine, Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

133.80 CHF - 381.34 CHF

Spezifikation

Antigen CEP164
Konzentration 0.29 mg/mL
Anwendungen Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
Klassifikation Polyclonal
Konjugat Unconjugated
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
16851765
Unterlagen ansehen Aktionsdetails
Proteintech
22227-1-AP-20UL
20 μL
133.80 CHF
20 Mikroliter
Lager vorrätig
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16841765
Unterlagen ansehen Aktionsdetails
Proteintech
22227-1-AP-150UL
150 μL
381.34 CHF
150 Mikroliter
Lager vorrätig
Sie sich ein, um den Lagerbestand zu sehen
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Beschreibung

Beschreibung

CEP164 was initially identified as a centrosomal protein, but other studies have indicated that it also plays a role in the formation of primary cilia, the microtubule-based sensory antennae projecting from the surface of many eukaryotic cells as well as in DNA damage response acting as a mediator protein. CEP164 interacts with both ATR and ATM, proteins that trigger a number of cellular responses including the initiation of DNA damaged-induced cell cycle checkpoints. It is phosphorylated upon replication stress, ultraviolet (UV) radiation, and ionizing radiation silencing of CEP164 significantly reduces the DNA damage-induced phosphorylation of several proteins in the DNA damage-activated signaling cascade and compromises cell survival after UV damage. At least two isoforms of CEP164 are known to exist.
Spezifikation

Spezifikation

CEP164
Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
Unconjugated
Rabbit
Canine, Human
Q9UPV0
22897, 489389
CEP164 Fusion Protein Ag17570
Primary
-20°C
CEP164
0.29 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
centrosomal protein 164kDa, Centrosomal protein of 164 kDa, CEP164, KIAA1052
CEP164
IgG
Antigen Affinity Chromatography
Antibody
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Sicherheitsdatenblatt (SDS)
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Dokumentation

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